Final answer:
Calcium channel blockers have the least effect on Intracranial Pressure (ICP) among antihypertensive medications.
Step-by-step explanation:
The antihypertensive medication that has the least effect on Intracranial Pressure (ICP) is calcium channel blockers.
Calcium channel blockers work by relaxing the blood vessels and reducing the overall resistance to blood flow, which helps to decrease blood pressure. They do not have a significant impact on Intracranial Pressure (ICP) as compared to other antihypertensive medications.
On the other hand, beta-blockers, ACE inhibitors, and diuretics may have certain physiological effects that can potentially increase Intracranial Pressure (ICP).