Question

In osteogenesis imperfecta, thermoregulation may be affected due to:

a) Increased sweat gland activity
b) Decreased muscle mass
c) Impaired collagen synthesis
d) Enhanced vasoconstriction

Answer 1

c) Impaired collagen synthesis

Osteogenesis imperfecta (OI) is a genetic disorder that affects the production of collagen, resulting in fragile bones. Individuals with OI may experience thermoregulation issues due to impaired collagen synthesis.

Step-by-step explanation:

Osteogenesis imperfecta (OI) is a genetic disorder characterized by fragile and easily fractured bones. It is caused by a mutation that affects the body's production of collagen, a critical component of bone matrix. In addition to bone deformities and short stature, individuals with OI may also experience thermoregulation issues. The correct answer is c) impaired collagen synthesis. Since collagen is an important structural protein, its deficiency can affect sweat gland function and vasoconstriction, leading to difficulties in maintaining body temperature.