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Which is the most common mitochondrial disorder (of 4 listed)?

User Javex
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Final answer:

Hypertrophic cardiomyopathy is the most common mitochondrial disorder among the options provided. It affects the heart muscle and is related to energy production deficiencies due to faulty cellular respiration. Diagnosis and treatment require specialized knowledge in mitochondrial medicine.

Step-by-step explanation:

The most common mitochondrial disorder among the four listed options is hypertrophic cardiomyopathy. This condition, which can be linked to mitochondrial dysfunction, is a type of heart disease that involves thickening of the heart muscle and can lead to various complications. Mitochondrial diseases like this arise from mutations in either nuclear or mitochondrial DNA, leading to a decrease in the production of energy within the body's cells. This affects critical reactions of cellular respiration, particularly oxidative phosphorylation which is essential for energy production.

A mitochondrial disease physician is specialized in diagnosing and treating these complex diseases. The variability in symptoms and the age of onset in mitochondrial diseases are common, as seen with Jasmin and her niece, who have the same disease but different symptoms and ages of diagnosis.

While there are many mitochondrial disorders with varying degrees of prevalence and symptomatology, it is important to note that conditions like lactase persistence and G6PD deficiency are not mitochondrial diseases. G6PD deficiency, for instance, is the most common enzyme-deficiency disorder and is not directly related to mitochondrial function but rather to red blood cell stability.

User Aram Becker
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