Question

41 y/o without family h/o corticocerebellar degeneration presents with 3-month h/o ataxia of gait/limbs, dysarthria, and progressive nystagmus. MRI and CSF normal.

1) Antibody panel with presence of ?
2) What type of tumor is likely present?

Answer 1

The presence of specific antibodies should be checked to determine the cause of the symptoms. Paraneoplastic tumors may be the likely cause of the symptoms.

Step-by-step explanation:

Based on the symptoms described, the presence of ataxia of gait, limbs, dysarthria, progressive nystagmus, and normal MRI and CSF results, one possible cause of these symptoms could be an autoimmune or paraneoplastic condition. To confirm the cause, an antibody panel should be conducted to identify the presence of any specific antibodies that may indicate an underlying autoimmune or paraneoplastic process. The specific antibodies to check for would depend on the suspected condition or associated tumor.

The likely type of tumor that could be present in this case is a paraneoplastic tumor. Paraneoplastic tumors are a group of rare tumors that are associated with an autoimmune response triggered by the presence of cancer cells. These tumors can present with various neurological symptoms, including ataxia. As mentioned earlier, an antibody panel can help identify the specific antibodies associated with paraneoplastic tumors.