Final answer:
Positive allosteric modulators of neurotransmitter-gated ion channels enhance the activity of these channels by binding to a different site on the channel protein.
Step-by-step explanation:
Positive allosteric modulators of neurotransmitter-gated, multimeric ion channels enhance the activity of these channels by binding to a different site on the channel protein. When the modulator binds, it causes a conformational change in the channel protein, leading to increased opening and activity of the ion channel. This results in an increased influx of ions, such as sodium or calcium, into the postsynaptic cell, which can have various effects on neuronal function.