Question

What are lab results that support a vaso-occlusive crisis (pain crisis) in sickle cell patients?

Answer 1

Lab results that support a vaso-occlusive crisis in sickle cell patients include elevated levels of lactate dehydrogenase and bilirubin, an elevated white blood cell count, an elevated C-reactive protein level, and an elevated reticulocyte count.

Step-by-step explanation:

Vaso-occlusive crisis, also known as a pain crisis, is a common complication of sickle cell disease. It occurs when sickle-shaped red blood cells block the tiny blood vessels, leading to pain and organ damage. There are certain lab results that can support a vaso-occlusive crisis in sickle cell patients:

1. Elevated white blood cell count (WBC): Inflammation and infection can often accompany a pain crisis, causing an increase in WBC count.
2. Elevated C-reactive protein (CRP): CRP is a marker of inflammation and can be elevated during a pain crisis.
3. Elevated reticulocyte count: Reticulocytes are immature red blood cells released from the bone marrow in response to anemia. During a pain crisis, the bone marrow releases more reticulocytes than usual.