Final answer:
The zero reference line on an aircraft fuselage is the location designated by the manufacturer, typically at the nose or firewall, from which positions and distances along the fuselage sections are measured.
Step-by-step explanation:
In the context of aircraft design, the location on the fuselage designated by the manufacturer as the zero reference line is typically at the nose but can also be at the firewall or another location. This reference line is used to designate positions and measure distances along the fuselage sections.