Question

A three-year-old girl was brought by her parents to the ED because of a possible ingestion. The girl was caught with an open bottle of amitriptyline although the mother is not sure how many tablets were missing. The girl did not experience any mental status changes, vomiting, abdominal pain, or fever. She arrived at the ED within 60 minutes of her possible ingestion. On examination, she is alert, active, with tachycardia, dry mucous membranes, and pupils 5-6 mm. Which of the following is the antidote for this type of ingestion?

-AFlumazenil
-BN-acetylcysteine
-CNaloxone
-DSodium bicarbonate

Answer 1

The antidote for amitriptyline ingestion is sodium bicarbonate. It works by raising the pH of the blood, reducing the toxic effects of the drug.

Step-by-step explanation:

The antidote for amitriptyline ingestion is sodium bicarbonate. Sodium bicarbonate is used to treat tricyclic antidepressant (TCA) overdose, which includes amitriptyline. It works by raising the pH of the blood, reducing the toxic effects of the drug. In cases of TCA overdose, sodium bicarbonate is administered intravenously.