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True/False. According to the 2010 ADA guidelines, HbA1C percent can be used as an assay to diagnose diabetes.

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Final answer:

True, the HbA1C percent is used according to the 2010 ADA guidelines for diagnosing diabetes. It reflects the average blood glucose over the past few months and does not require fasting, though certain medical conditions can impact its levels.

Step-by-step explanation:

The statement is true. According to the 2010 ADA guidelines, the Hemoglobin A1c (HbA1C) percent can indeed be used as an assay to diagnose diabetes mellitus. Hemoglobin A1c is the main form of glycosylated hemoglobin and indicates the average blood glucose level over the previous 3 to 4 months. When glucose binds to the hemoglobin in red blood cells, higher levels of HbA1c are seen in individuals with poor glucose control, suggesting diabetes mellitus.

It is important to recognize the utility of the HbA1c test as it's not affected by short-term fluctuations and doesn't require fasting. However, conditions such as kidney failure, excessive alcohol intake, hypertriglyceridemia, and blood disorders can affect HbA1c levels. As per the guidelines, a HbA1c level of 6.5% or higher is indicative of diabetes. Patients with well-controlled diabetes try to keep their HbA1c close to 7% to prevent complications, whereas levels over 9% show poor control. Testing HbA1c is typically recommended every 3 to 6 months.

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