Final answer:
A cherry-red spot on a fundal exam should prompt consideration of central retinal artery occlusion, Tay-Sachs disease, and other diseases such as sialidosis or Niemann-Pick disease.
Step-by-step explanation:
When a fundal exam reveals a cherry-red spot, the diagnosis that should be considered includes central retinal artery occlusion (CRAO) or a rare inherited metabolic disorder known as Tay-Sachs disease, among others. The cherry-red spot is a classic sign in which the central area of the retina, called the fovea, stands out as a bright red spot against the retina. Other conditions, such as sialidosis or Niemann-Pick disease, may also present with a cherry-red spot on fundal examination. A comprehensive medical history, additional symptoms, and further diagnostic tests would help narrow down the diagnosis and guide appropriate treatment.