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What teratogenic effects do ACE inhibitors/ARBs have?

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Final answer:

ACE inhibitors and ARBs can have teratogenic effects on the fetus, causing fetal renal failure, oligohydramnios, pulmonary hypoplasia, limb contracture, and cranial bone abnormalities.

Step-by-step explanation:

ACE inhibitors and ARBs (Angiotensin Receptor Blockers) can have teratogenic effects on the fetus. These medications, which are commonly prescribed for high blood pressure, can cause fetal renal failure, oligohydramnios (low amniotic fluid levels), and subsequent pulmonary hypoplasia (underdeveloped lungs) and limb contracture (abnormal limb positioning). In addition, fetal cranial bone abnormalities can also occur. It is important for pregnant women to avoid taking ACE inhibitors or ARBs unless specifically instructed by their healthcare provider.

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