Final answer:
The major risk factor for bladder cancer is smoking tobacco, which is a significant and preventable risk factor that can lead to the development of cancer by damaging the bladder lining.
Step-by-step explanation:
One major risk factor for bladder cancer is smoking tobacco. Smoking is a significant environmental risk factor that increases the risk of various cancers, including bladder cancer. The harmful chemicals in cigarette smoke may damage the lining of the bladder, which can lead to the development of cancer. This is a changeable risk factor, meaning that quitting smoking can significantly reduce the risk of developing bladder cancer.
Additionally, exposure to certain types of environmental pollutants and industrial chemicals has also been linked to an increased risk of bladder cancer. However, smoking remains one of the most important but preventable risk factors for this disease.