Final answer:
The procedure that will increase the DRG assignment the most for a patient with septicemia is ventilator management for 106 consecutive hours (DRG 96.72).
Step-by-step explanation:
The procedure that will increase the DRG assignment the most for a patient with a principal diagnosis of septicemia is Ventilator management for 106 consecutive hours (DRG 96.72). Septicemia is a serious infection that can lead to organ failure and requires intensive care. Ventilator management is a complex and resource-intensive procedure often associated with severe infections and critical illness, which results in a higher DRG assignment.