Question

Which of the following neuromuscular blocker is most likely to cause rapid muscle contractions referred to as fasciculations?

A) Atracurium
B) Mivacurium
C) Rocuronium
D) Vecuronium
E) Succinylcholine

Answer 1

Succinylcholine is the neuromuscular blocker most likely to cause rapid muscle contractions known as fasciculations.

Step-by-step explanation:

The neuromuscular blocker most likely to cause rapid muscle contractions referred to as fasciculations is Succinylcholine (E). Unlike other neuromuscular blocking agents like Atracurium, Mivacurium, Rocuronium, and Vecuronium, which block the transmitter action of acetylcholine without depolarizing the neuromuscular endplate, Succinylcholine acts as a depolarizing agent. It mimics acetylcholine at the neuromuscular junction, causes initial depolarization (leading to fasciculations), and then produces sustained depolarization which results in muscle relaxation and paralysis. This is in contrast to other agents, which are considered non-depolarizing and do not cause these initial rapid contractions.