Final answer:
The staff nurse must include the client's marital status in the mandatory report related to a newly diagnosed E. coli infection. However, race, sexual orientation, and religion are not relevant or necessary for the management of the infection.
Step-by-step explanation:
In the mandatory report related to a client's newly diagnosed Escherichia coli (E. coli) infection, the staff nurse must include the client's marital status. This information is important for monitoring the spread of infectious diseases and identifying any potential risk factors or sources of infection. However, the nurse does not need to include the client's race, sexual orientation, or religion in the report as these factors are not relevant or necessary for the management of an E. coli infection.