Final answer:
A connective tissue disorder associated with aortic aneurysm is:B. Marfan's syndrome.
Step-by-step explanation:
A connective tissue disorder associated with aortic aneurysm is Marfan's syndrome (B). Marfan's syndrome is a genetic disorder that affects the connective tissue and can lead to abnormalities in various organs, including the heart and blood vessels. Individuals with Marfan's syndrome are at an increased risk of developing aortic aneurysms due to the weakened and less elastic nature of their connective tissue.
The genetic mutation associated with Marfan's syndrome affects the fibrillin-1 gene, a crucial component of the connective tissue. This leads to structural weaknesses in the aortic wall, making it prone to dilation and the formation of aneurysms. Aortic aneurysms in Marfan's syndrome can be life-threatening if not monitored and managed appropriately.
Understanding the specific connective tissue disorders associated with aortic aneurysms is essential for healthcare professionals involved in the care of individuals with these conditions.
While other connective tissue disorders such as Ehlers-Danlos syndrome, Pseudoxanthoma elasticum, and Turner's syndrome may have cardiovascular implications, Marfan's syndrome is particularly known for its association with aortic aneurysms, emphasizing the importance of genetic testing and cardiovascular surveillance in affected individuals.