Final answer:
Comatose patients should receive oral care at least twice a day to maintain hygiene and prevent infections.
Step-by-step explanation:
Patients who are comatose require regular oral care to maintain oral hygiene and prevent infections. As such, oral care should be provided on a routine basis. It is typically recommended that oral care be done at least twice a day for comatose patients, once in the morning and once in the evening, similar to the regimen suggested for the stroke patients using the new software program in the studies mentioned. This helps ensure the mouth is kept clean and moist, and prevents the buildup of bacteria.