Question

The congenital heart defect most often associated with Down's syndrome (trisomy 21) is:

A. Coarctation of the aorta
B. Endocardial cushion defect
C. Peripheral pulmonary stenosis
D. Tetralogy of Fallot

Answer 1

The congenital heart defect most commonly associated with Down's syndrome is the Endocardial cushion defect, a condition affecting the heart's septum and valves.

Step-by-step explanation:

The congenital heart defect most often associated with Down's syndrome (trisomy 21) is an Endocardial cushion defect. This condition, also known as an atrioventricular septal defect, involves abnormalities in the heart's structure affecting the atrial septum, ventricular septum, and valves that lie between the upper and lower chambers of the heart. Individuals with Down syndrome are at a higher risk for this particular congenital heart defect, contributing to a variety of cardiac issues that require careful management and potential surgical intervention.