Final Answer:
Signs and symptoms of significant tricuspid regurgitation include all the following EXCEPT C. Pulsus paradoxus.
Step-by-step explanation:
Pulsus paradoxus is not typically associated with significant tricuspid regurgitation. Tricuspid regurgitation is characterized by the backward flow of blood from the right ventricle into the right atrium during the contraction of the heart. The regurgitation leads to various clinical manifestations, such as hepatomegaly (option A), jugular venous distention (option B), and right ventricular failure (option D).
Hepatomegaly is the enlargement of the liver, often seen in conditions of elevated right-sided heart pressures, such as tricuspid regurgitation. Jugular venous distention is a result of increased venous pressure, another common consequence of significant tricuspid regurgitation. Right ventricular failure, indicated by symptoms like peripheral edema and ascites, can also be a consequence of chronic tricuspid regurgitation.
Pulsus paradoxus (option C) is more commonly associated with conditions like cardiac tamponade or severe asthma exacerbations, where there is an exaggerated drop in blood pressure during inspiration. It is not a typical feature seen in isolation with significant tricuspid regurgitation.
In summary, recognizing the signs and symptoms associated with tricuspid regurgitation is essential for diagnosing and managing this valvular disorder. However, the presence of pulsus paradoxus would lead healthcare professionals to consider alternative diagnoses or concurrent conditions.