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Peter Mitchell proposed the hypothesis that describes how proton-motive force, oxidation of NAD and FADH2, and proton gradient are coupled.

a) Proton-motive force; oxidation of NAD and FADH2; proton gradient.

b) Oxidation; reduction of NAD and FADH2; electron transport.

c) pH gradient; electron transport; ATP synthesis.

d) Chemiosmotic; electron transport; ATP synthesis.

User Tooony
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Final answer:

The correct answer is option a. The chemiosmotic mechanism proposed by Peter Mitchell describes how the proton-motive force, oxidation of NAD and FADH2, and proton gradient are coupled in the process of oxidative phosphorylation.

Step-by-step explanation:

The chemiosmotic mechanism proposed by Peter Mitchell describes how the proton-motive force, oxidation of NAD and FADH2, and proton gradient are coupled in the process of oxidative phosphorylation. The movement of electrons through the electron transport chain in the mitochondria results in the pumping of hydrogen ions (protons) across the inner mitochondrial membrane, creating a proton gradient.

This proton gradient, along with the difference in electric potential, is known as the proton-motive force. It is this proton-motive force that drives ATP synthesis through the enzyme ATP synthase.

User Dmitry Sazonov
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