Question

Classify the descriptions to demonstrate your understanding of various cancers that have a possible microbial cause.

1.Lymphoma
2.Liver Cancer
3. Breast Cancer
4. Cervical Cancer
5. Gastric Cancer
6. Colorectal Cancer

a) Colibactin is produced and damages DNA, causing mutations
b) Can be caused by a lack of "good" bacteria
c) Can be linked to E. coli in gut carrying specific gene
d) Can be caused by several types of HPV
e) Can be prevented by a vaccine given to pre- adolescents
f) Chronic inflammation of hepatocytes leads to increased division for repair and increased mutation rate
g) Can be caused by HBV or HCV
h) Has been linked to H. pylori infection
i) Viral genes produce mimic proteins that override the checkpoints of cell cycle
j) CagA protein activates oncogenes and inactivates p53
k) EBV enters the latent state in B lymphocytes
l) A Mediterranean diet may decrease chances whereas a high-fat diet may increase chances Reset

Answer 1

Various cancers with possible microbial causes include lymphoma, liver cancer, breast cancer, cervical cancer, gastric cancer, and colorectal cancer.

Step-by-step explanation:

1. Lymphoma: Can be caused by several types of HPV, which produce mimic proteins overriding cell cycle checkpoints.
2. Liver Cancer: Chronic inflammation of hepatocytes leads to increased division and mutation rate. Can be caused by HBV or HCV.
3. Breast Cancer: Can be caused by a lack of 'good' bacteria. a Mediterranean diet may decrease chances whereas a high-fat diet may increase chances.
4. Cervical Cancer: Can be caused by several types of HPV, which can be prevented by a vaccine given to pre-adolescents.
5. Gastric Cancer: Has been linked to H. pylori infection. Chronic gastritis caused by H. pylori can lead to ulcers and stomach cancer.
6. Colorectal Cancer: Colibactin produced by E. coli damages DNA, causing mutations.