Final answer:
The statement is false; the completed polypeptide is released from the tRNA in the P site, not the E site, during translation.
Step-by-step explanation:
The statement that the completed polypeptide is released from the tRNA that is in the E site is false. During translation, once a stop codon is encountered, and release factors trigger the release of the polypeptide, it is actually attached to the tRNA in the P site. The release factors induce the addition of a water molecule to the carboxyl end of the polypeptide, which effectively releases the polypeptide chain from the tRNA. The tRNA in the E site is the one that has already transferred its amino acid to the polypeptide chain and is expelled from the ribosome without its attached amino acid.