Final answer:
The first step in RBC formation from a hemocytoblast is the differentiation of a myeloid stem cell to a proerythroblast, part of the complex process called hemopoiesis.
Step-by-step explanation:
The first step in the formation of a mature red blood cell (RBC) from a hemocytoblast is the differentiation of a myeloid stem cell into a proerythroblast. This process is part of hemopoiesis, which involves several stages of precursor cells, including proerythroblasts that eventually become reticulocytes. Reticulocytes continue to mature and eventually eject their nucleus and most other organelles to become erythrocytes, which are the most abundant formed elements in blood.