Question

Identify the benefit of the inhalation route.

1) Faster onset of action
2) Avoidance of first-pass metabolism
3) Higher bioavailability
4) All of the above

Answer 1

The inhalation route provides benefits such as a faster onset of action, avoidance of first-pass metabolism, and higher bioavailability, making it effective for systemic drug delivery.

Step-by-step explanation:

The benefit of the inhalation route of drug administration includes: 1) Faster onset of action, 2) Avoidance of first-pass metabolism, and 3) Higher bioavailability. These factors contribute to the efficacy of inhalation as a route for delivering systemic medications. For instance, unlike oral administration, inhalation allows drugs to be absorbed directly into the bloodstream through the lungs, therefore bypassing the digestive system and liver where first-pass metabolism can occur. This can result in a faster onset of action as the drug reaches its target sites more rapidly. Additionally, drugs administered via inhalation can often achieve higher plasma levels when compared to oral or intramuscular routes, ensuring better effectiveness for treatment, especially in the case of infections or conditions requiring quick therapeutic response.