Final answer:
The best description of what happens after phagocytosis is that a lysosome combines with the vacuole to digest the solid material, followed by expulsion of soluble debris from the cell.
Step-by-step explanation:
Once solid material is phagocytized and taken into a vacuole, the correct description of what happens next is: A lysosome combines with the vacuole and digests the enclosed solid material. This process begins when a phagocyte encounters a pathogen and engulfs it with a portion of its plasma membrane, forming a phagosome. The phagosome then fuses with a lysosome to form a phagolysosome, where digestive enzymes and acids kill and digest the pathogen. The final step involves expelling the soluble debris from the destroyed pathogen through exocytosis, completing the process of phagocytosis.