Question

Which type of T cell is involved in activating macrophages and stimulating development of cytotoxic T cells?

1) TH₂ cells
2) TH1 cells
3) Cd₈⁺ T cells
4) Treg cells

Answer 1

TH1 cells are responsible for activating macrophages and stimulating the development of cytotoxic T cells by secreting cytokines.

Step-by-step explanation:

The type of T cell involved in activating macrophages and stimulating the development of cytotoxic T cells is TH1 cells. These cells secrete cytokines that not only help to stimulate the immune response against intracellular pathogens by activating macrophages but also enhance the killing efficiency of cytotoxic T cells (Tc cells). The process involves TH1 cells recognizing specific antigens presented by MHC class II complexes on antigen-presenting cells (APCs), which then leads to the secretion of cytokines that provide the necessary signals to activate macrophages and support the growth and differentiation of cytotoxic T cells into memory T cells, increasing their readiness to respond to subsequent encounters with the pathogen.