Final answer:
Option 1) and Option 2). Humans become sick from predatory fish with accumulated toxins from polluted water and contaminated food. Mercury, lead, and cadmium are examples of toxic substances that get biomagnified in the food chain.
Step-by-step explanation:
Predatory fish that have accumulated toxins from contaminated food and water can make humans sick. Dead zones are produced in aquatic ecosystems by water pollution brought on by untreated sewage, chemicals, and heat, and the pollutants are absorbed through the food chain. Human consumption of contaminated food and water can result in the ingestion of toxic substances such as lead, cadmium, and mercury, which can cause illness or even death.