Question

Which of the following is not a characteristic of native antigen recognized by T cells?

1) peptides ranging between 8 and 25 amino acids in length
2) binding to major histocompatibility complex (MHC) molecules
3) activation of T cell receptors
4) presence of specific antigenic determinants

Answer 1

The characteristic of native antigens not recognized by T cells is the presence of specific antigenic determinants.

Step-by-step explanation:

The characteristic of native antigen recognized by T cells that is not present is the presence of specific antigenic determinants. T cells recognize antigens on the surface of specialized cells called antigen-presenting cells (APCs), which internalize antigens, enzymatically cleave them into smaller pieces, and present them on the surface associated with major histocompatibility complex (MHC) molecules. The combination of the MHC molecule and the processed antigen fragment is recognized by the T cell receptor, leading to T cell activation.