Question

Which of the following is/are not encoded on chromosome 6 in the HLA complex?

1) HLA-A
2) HLA-B
3) HLA-C
4) HLA-D

Answer 1

None of the options provided (HLA-A, HLA-B, HLA-C, HLA-D) are correct because they are all encoded within the HLA complex on chromosome 6, which includes both the MHC class I genes (HLA-A, HLA-B, HLA-C) and the MHC class II genes (HLA-DP, HLA-DQ, HLA-DR).

Step-by-step explanation:

The student's question pertains to the human leukocyte antigen (HLA) complex and which of the specified HLA types are not encoded on chromosome 6. All the HLA types mentioned in the options - HLA-A, HLA-B, HLA-C, and HLA-D - are part of the HLA complex, which is indeed located on chromosome 6. However, to specifically address the question, none of these options are correct because they are all encoded within the HLA complex on chromosome 6. The HLA-A, HLA-B, and HLA-C are part of the MHC class I genes, while HLA-D refers to MHC class II genes, which include HLA-DP, HLA-DQ, and HLA-DR.