Final answer:
The Creatinine Clearance (CrCl) equation for males is CrCl = (U x V) / B, reflecting kidney function by measuring the glomerular filtration rate. It is corrected for body surface area (BSA), and normal values are 90-139 ml/min for males under 40 years old.
Step-by-step explanation:
Creatinine Clearance Equation for Males (CrCl)
The Creatinine Clearance (CrCl) equation is an important medical calculation used to measure the glomerular filtration rate (GFR), which reflects kidney function. For males, this equation can be represented as:
CrCl = (U x V) / B
Where:
- 'U' is the concentration of creatinine in urine
- 'V' is the volume of urine excreted per minute
- 'B' is the concentration of creatinine in the blood plasma
Creatinine Clearance is corrected for body surface area (BSA) to allow comparison between individuals. The BSA can be calculated using the formula:
BSA = 0.007184 × W0.425 × H0.725 (Where 'W' is weight in kg and 'H' is height in cm)
For a 24-hour urine collection, normal CrCl values are approximately 90-139 ml/min for adult males under 40 years old. These values typically decrease with age.