Final answer:
The Creatinine Clearance equation for females is calculated by [(U x V) / B] x (1.73 / BSA), where U is urine creatinine concentration, V is urine flow rate, B is blood creatinine, and BSA is Body Surface Area. Normal values for women under 40 are 80-125ml/min, decreasing with age.
Step-by-step explanation:
The Creatinine Clearance equation (CrCl) for females, which is used to measure Glomerular Filtration Rate (GFR), can be represented with the following formula:
CrCl (ml/min) = [(U x V) / B] x (1.73 / BSA)
where U is the urine creatinine concentration, V is the urine flow rate, B is the creatinine concentration in plasma, and BSA stands for Body Surface Area.
The average BSA is typically estimated using the formula: BSA = 0.007184 × W0.425 × H0.725, and for an average adult female, this is around 1.7 m2. To calculate the BSA-adjusted CrCl, the result is often compared to the average sized person as ml/min/1.73 m2.
For adult females less than 40 years old, normal creatinine clearance values are 80-125ml/min and these values decrease with age. Typically, there is a decline of 6.5 ml/min for each subsequent decade of life.