Final answer:
The renowned French designer who created the 'cone bra' for Madonna and designed for Marilyn Manson is Jean Paul Gaultier, notable for his avant-garde fashion and use of unconventional models.
Step-by-step explanation:
The French Haute Couture and RTW designer known for using unconventional models, designing the 'cone bra' for Madonna, creating designs based on the muscular system, and crafting costumes for Marilyn Manson is Jean Paul Gaultier. Jean Paul Gaultier is acclaimed for his avant-garde and conceptual approach to fashion, often challenging the norms of the industry. His boundary-pushing designs and iconic pieces, such as the 'cone bra' worn by Madonna during her Blond Ambition Tour in 1990, have cemented his status as a pioneering designer in the world of haute couture and ready-to-wear fashion.