Final answer:
pH and Binding Affinity are inversely proportional, specifically within the Bohr effect framework, affecting how oxygen binds to hemoglobin. An increase in acidity (lower pH) reduces oxygen's affinity for hemoglobin, while a higher pH strengthens this affinity.
Step-by-step explanation:
The relationship between pH and Binding Affinity in the context of the Bohr effect is one where they are inversely proportional. This means that as the pH of blood decreases, becoming more acidic, the affinity of oxygen for hemoglobin decreases, promoting the dissociation of oxygen from hemoglobin. Conversely, as the pH increases, indicating a more basic environment, the affinity of oxygen for hemoglobin also increases, inhibiting its dissociation. The presence of carbon dioxide and byproducts of cellular metabolism like lactic acid contribute to the reduction in pH, thereby affecting hemoglobin's oxygen-binding affinity.
Regarding the multiple-choice options provided, the correct answer is that the blood pH will drop and hemoglobin affinity for oxygen will decrease (option c).