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V.L. is prescribed tamoxifen (Nolvadex) to be started upon discharge. You teach V.L. about this new drug and explain that while she is taking this drug she?

1) will be unable to experience sexual satisfaction with her husband.
2) may experience hot flashes, mood swings, and vaginal discharge.
3) may experience decreased visual acuity that is not a cause for concern.
4) should continue to take her hormone therapy to treat the hot flashes.

1 Answer

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Final answer:

Doctors may hesitate to recommend hormone replacement therapy (HRT) due to risks such as increased incidents of cancer and cardiovascular events, as shown in studies like the Women's Health Initiative. Ongoing debates on the efficacy and safety of HRT highlight its complex nature, and guidelines recommend cautious use with monitoring.

Step-by-step explanation:

The side effects of menopause can be diminished by hormone replacement therapy (HRT). Yet, doctors may be reluctant to recommend HRT due to its potential negative side effects, such as increased risk of stroke, heart attack, blood clots, various types of cancer (breast, ovarian, endometrial), gall bladder disease, and possibly dementia. Despite HRT providing protection from issues like colon cancer, osteoporosis, and heart disease, the risks sometimes outweigh the benefits, particularly with regard to breast cancer as seen in historical studies.

Studies like the Women's Health Initiative have shown that estrogen-only HRT led to a higher risk of breast cancer, challenging its cardio-protective effects. Ongoing research continues to examine the age factor in hormone therapy studies, suggesting that younger populations may benefit more than older ones. The current guidelines advise using HRT mainly to reduce menopausal symptoms such as hot flashes, prescribing the lowest effective dose for the shortest duration, and emphasize the need for regular health checks during treatment.

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