Final answer:
Mr. Smith is suffering from acromegaly, a disorder characterized by excessive production of growth hormone in adults, resulting in enlargement of bones in the skull, hands, and feet.
Step-by-step explanation:
Mr. Smith is suffering from acromegaly. Acromegaly is a disorder caused by excessive production of growth hormone (GH) in adults. In this condition, a tumor in the adenohypophysis leads to increased levels of GH, resulting in enlargement of bones in the entire skull, hands, and feet, as well as thickening of the skin. The broadened skull, hands, fingers, and thickened soft tissue are characteristic features of acromegaly.