Among the given options, feelings of hopelessness would best support a diagnosis of depression for the patient who has symptoms like weight loss, insomnia, and fatigue. Other listed symptoms suggest conditions that are not typically associated with depression.
The patient's complaints of insomnia, indecisiveness, and fatigue paired with significant weight loss and worries about future job prospects suggest the presence of depressive symptoms. Within the provided options, feelings of hopelessness would best support a diagnosis of depression in this case, as it directly aligns with the emotional symptoms of the disorder.
The other symptoms listed such as weight gain, increased appetite, and excessive energy are less indicative of depression and, in some cases, may suggest other conditions or states such as anxiety or hyperthyroidism.
Depression is characterized by a range of symptoms including profound sadness, changes in sleep and eating patterns, withdrawal from social interactions, loss of interest in previously pleasurable activities, and physical changes such as weight loss or gain. In this scenario, the patient's feelings dovetail with the sense of pessimism, worries about the future, and changes in physical health that accompany major depressive disorder. This highlights the importance of a comprehensive evaluation to support an accurate diagnosis and appropriate treatment.