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What happens during the coagulation phase after a platelet forms?

User Hans Glick
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Final answer:

After a platelet plug is formed, the coagulation phase takes place where activated platelets aid in forming a stable fibrin clot that halts blood loss and allows for tissue repair.

Step-by-step explanation:

Coagulation Phase and Platelet Function

After a platelet plug forms, the coagulation phase of hemostasis begins. Activated platelets change shape, becoming spiked and sticky, which allows them to aggregate at the injury site and form a temporary seal. These platelets release substances that activate more platelets, and initiate a series of reactions leading to the formation of fibrin. Fibrinogen, a blood protein, is converted into fibrin during this process. Fibrin forms a mesh that traps more platelets and erythrocytes, thus producing a stable clot. This clotting process is enhanced by various clotting factors, many of which depend on vitamin K for their activity. The stable fibrin clot - also referred to as a fibrin plug or fibrin clot - stops blood loss and lasts for a number of days, providing time for tissue repair.

User Ignat Insarov
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