Final answer:
The settlers from Europe brought diseases like smallpox to America, which had a devastating impact on the Native American population.
Step-by-step explanation:
When the settlers from Europe came to America, they inadvertently brought diseases such as smallpox, influenza, measles, and typhus, which had devastating consequences for the Native American population. The Europeans had developed immunity to these diseases, but the Native Americans had no prior exposure and therefore had no natural defenses against them. As a result, these diseases caused widespread sickness and death among the Native Americans, leading to a significant decline in their population.