Final answer:
The statement 'cartilage tissue forms and is replaced by bone tissue' is NOT TRUE about intramembranous ossification. Bone develops directly from mesenchymal tissue, not from a cartilage template as in endochondral ossification. Therefore, the incorrect option is A.
Step-by-step explanation:
The statement about intra-membranous ossification that is NOT TRUE is that cartilage tissue forms and is replaced by bone tissue. Intra-membranous ossification does not involve a cartilaginous template. Instead, this process involves the development of bone from mesenchymal connective tissue. Bones such as the flat bones of the face, most cranial bones, and clavicles are formed this way. Cartilage is replaced by bone during endochondral ossification, which is responsible for forming bones at the base of the skull and long bones, and takes longer compared to intramembranous ossification.