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What is the sequence between succinyl CoA to ATP?

User Kiennt
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Final answer:

The sequence from succinyl CoA to ATP in the citric acid cycle involves the conversion of GDP to GTP by succinyl-CoA synthetase, which is then converted to ATP. The subsequent steps produce FADH2 and ultimately regenerate oxaloacetate.

Step-by-step explanation:

The sequence between succinyl CoA to ATP is part of the citric acid cycle, which is a central component of cellular respiration. In step five of the cycle, the energy stored in succinyl CoA is harnessed to convert guanosine diphosphate (GDP) into guanosine triphosphate (GTP), a process catalyzed by succinyl-CoA synthetase. GTP then transfers its terminal phosphate group to adenosine diphosphate (ADP), forming ATP. This reaction is facilitated by nucleoside phosphokinase.

Continuing with the cycle, succinyl CoA undergoes dehydrogenation to form succinate, through an enzyme-catalyzed reaction involving succinate dehydrogenase. This reaction produces FADH2 which, through the electron transport chain (ETC), contributes to the production of additional ATP. The remaining steps involve the hydration of fumarate to form L-malate and the regeneration of oxaloacetate, allowing the cycle to continue.

User ScottMcGready
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