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What does pyruvate carboxylase consume during gluconeogenesis?

1) ATP
2) NADH
3) Cl₃
4) Pyruvate

User Roco
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1 Answer

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Final answer:

During gluconeogenesis, pyruvate carboxylase consumes ATP to convert pyruvate into oxaloacetate, which is the beginning step in the pathway to synthesize glucose.

Step-by-step explanation:

The enzyme pyruvate carboxylase plays an essential role in gluconeogenesis, which is the metabolic process of synthesizing glucose from non-carbohydrate sources. During gluconeogenesis, pyruvate carboxylase consumes one molecule of ATP to convert pyruvate into oxaloacetate. This is a critical step as oxaloacetate is later converted to phosphoenolpyruvate and continues through the pathway to produce glucose. Therefore, the correct answer is ATP.