Question

What reagents would be required to synthesize hex-2-yne starting with acetylene?

A) HCl, Pd/C
B) NaNH₂, NH₃
C) Br₂, CH₃OH
D) H₂, Lindlar catalyst

Answer 1

To synthesize hex-2-yne from acetylene, the required reagents are NaNH₂ and NH₃, allowing for the formation and alkylation of a carbon anion.

Step-by-step explanation:

The reagents required to synthesize hex-2-yne starting with acetylene would be NaNH₂, NH₃ (Option B) as this would allow for deprotonation of acetylene and subsequent formation of a carbon anion, which could then undergo an alkylation reaction to form hex-2-yne. Although other options listed are commonly used in various organic transformations, they are not suitable for this specific synthesis.

HCl, Pd/C would add chlorine and hydrogen across the triple bond in a hydrochlorination reaction. Br₂, CH₃OH would add bromine to the multiple bonds in a halogenation reaction. H₂, Lindlar catalyst would hydrogenate the triple bond to a double bond, forming an alkene rather than the desired alkyne.