Final answer:
The incorrect statement regarding B-lymphocytes is that they can transform into NK cells; NK cells are not a direct product of B-lymphocyte differentiation.
Step-by-step explanation:
The statement regarding B-lymphocytes that is not correct is "B. Activated B-lymphocytes transform into plasma cells, memory B-lymphocytes, or NK cells." Naïve B-lymphocytes, upon activation, differentiate into plasma cells that produce antibodies and memory B-lymphocytes that provide long-lasting immunity. However, they do not differentiate into NK cells, as these are a separate type of lymphocyte involved in the innate immune response. B-lymphocytes must indeed be activated by helper T-lymphocytes (A), can transform into plasma or memory B-lymphocytes (B, except for the NK cells part), memory B-lymphocytes can live for months or even years (C), B-lymphocytes do produce immunoglobulins (D), and each B-lymphocyte is indeed specific to one particular antigen (E).