Final answer:
An increase in plasma concentrations of growth hormone promotes the increase in protein synthesis, leading to muscle growth and increased bone density.
Step-by-step explanation:
The primary effect of an increase in plasma concentrations of growth hormone is to promote the increase in protein synthesis. Growth hormone (GH) accelerates the rate of protein synthesis, particularly in skeletal muscle and bones. This leads to muscle growth and increased bone density. The indirect mechanism of GH action is mediated by insulin-like growth factors (IGFs), which stimulate the formation of new proteins.