Question

Creatine synthesis begins in the kidney and is completed in

A) Liver
B) Pancreas
C) Lungs
D) Muscles

Answer 1

A) Liver

Creatine synthesis begins in the kidney and is completed in the liver. The liver plays a crucial role in the synthesis of creatine, which is then transported to muscles and other tissues where it is utilized for energy metabolism.

Answer 2

Creatine synthesis begins in the kidney but is completed in the Liver, which is the main site of amino acid metabolism and responsible for several metabolic processes, including creatine synthesis.

Step-by-step explanation:

The synthesis of creatine begins in the kidney, with the process being completed in another organ. The correct answer to the question 'Creatine synthesis begins in the kidney and is completed in: A) Liver B) Pancreas C) Lungs D) Muscles?' is A) Liver. The liver takes up amino acids from the blood stream and performs various crucial metabolic processes, which includes the synthesis of creatine. Although the muscle is a significant site of creatine utilization, where the enzyme CPK converts creatine to creatine phosphate for energy supply during muscle contraction, the liver is responsible for completing creatine synthesis.

The liver's role extends beyond creatine synthesis; it is also the principal site of amino acid metabolism, gluconeogenesis, and inter-organ amino acid exchange, along with the transformation of vitamins to their active forms, such as vitamin D.