Final answer:
The chemokine receptor responsible for guiding activated T cell migration towards the interfollicular region to interact with B cells is CXCR5, which enables effective adaptive immune responses.
Step-by-step explanation:
The chemokine receptor that guides activated T cell migration towards the interfollicular region to increase their interactions with B cells is CXCR5. This interaction is crucial for the coordination of adaptive immune responses within germinal centers of lymph nodes. Once the T cells are in the interfollicular region, they can assist B cells in their activation and differentiation processes. For example, once a helper T cell is activated by an antigen-presenting cell (APC) via the MHC II receptor, it aids in activating relevant B cells. This is an essential part of the adaptive immune response where B cells undergo class switching and affinity maturation, leading to the production of high-affinity antibodies.