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Does phosphorylation confer a positive or negative charge to Phot1? How might this cause a change in shape in Phot1?

a. Positive charge; promoting folding
b. Negative charge; promoting unfolding
c. Positive charge; promoting unfolding
d. Negative charge; promoting folding

User Jonsuh
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1 Answer

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Final answer:

Phosphorylation adds a negative charge to Phot1, promoting a conformational change that results in protein folding. The correct answer is d. Negative charge; promoting folding.

Step-by-step explanation:

Phosphorylation typically confers a negative charge to a protein such as Phot1 by attaching a phosphate group to certain amino acids like serine, threonine, or tyrosine. This addition can cause a change in protein shape or conformation, which can alter the protein's activity, sometimes activating it or turning it off. In the case of Phot1, this phosphorylation-induced conformational change can promote a change in protein folding. Specifically, the answer to the question is d. Negative charge; promoting folding.

User Hyster
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