Question

Which of the following is NOT the role of molecular chaperones in the folding of

cellular proteins?
A. They assist proteins in folding into their correct conformations.
B. They help prevent formation of protein aggregates.
C. They specify the final three-
dimensional shape of proteins.
D. They catalyze the folding of proteins in the crowded environment of the cell.
E. They make the protein-folding process in the cell more reliable.

Answer 1

Molecular chaperones aid in protein folding and prevent aggregation but do not specify the final three-dimensional shape of proteins.

Step-by-step explanation:

The role of molecular chaperones in the folding of cellular proteins does not include specifying the final three-dimensional shape of proteins. Chaperones primarily assist in the correct folding of proteins by preventing incorrect interactions and aggregation that can occur in the cell's crowded environment. They do not determine the final structure of proteins; this information is inherent within the protein's sequence as determined by its corresponding mRNA. However, they play a crucial role in the protein-folding process by ensuring the conditions are conducive to correct folding and by providing a more reliable folding process in the cell.

• Molecular chaperones assist proteins in folding into their correct conformations.
• They help prevent the formation of protein aggregates.
• They make the protein-folding process in the cell more reliable.