Question

A reciprocal exchange between chromosomes 8 and 14 results in the ______ of the

c-myc gene into the Immunoglobulin H locus, resulting in abnormal over expression of c-myc

Answer 1

A reciprocal exchange between chromosomes 8 and 14 can result in the translocation of the c-myc gene into the Immunoglobulin H locus, leading to abnormal overexpression of c-myc.

Step-by-step explanation:

A reciprocal exchange between chromosomes 8 and 14 results in the translocation of the c-myc gene into the Immunoglobulin H locus. This translocation can lead to abnormal overexpression of the c-myc gene.

Translocations are large-scale mutations that occur when two separate chromosomal regions become abnormally fused at a characteristic location. In this case, the chromosomes involved are chromosomes 8 and 14. The abnormal fusion of these chromosomes results in the relocation of the c-myc gene, which leads to its overexpression.

Overexpression of the c-myc gene can have significant consequences, as it is an oncogene that plays a role in cell growth and proliferation. Abnormal overexpression of c-myc can contribute to the development of cancer.