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In brown adipose tissue, thermogenin inserts into the inner mitochondrial membrane and serves to___

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Thermogenin in brown adipose tissue inserts into the inner mitochondrial membrane to promote nonshivering thermogenesis, which is the generation of heat rather than ATP. This is vital for maintaining body temperature, particularly in newborns and those living in colder climates.

Step-by-step explanation:

In brown adipose tissue, thermogenin inserts into the inner mitochondrial membrane and serves to enable a process called nonshivering thermogenesis. Thermogenin, also known as uncoupling protein 1 (UCP1), is responsible for heat production instead of ATP during cellular respiration. By allowing protons (H+) to re-enter the mitochondrial matrix without driving ATP synthesis, it dissipates the proton gradient, releasing energy as heat. This mechanism is crucial for newborns and animals adapted to cold climates, as it provides a rapid means of body warming without shivering.

Specifically, brown adipose tissue, which contains these heat-producing mitochondria, can be found in regions like the neck and around the kidneys, especially in newborns, who rely on it for maintaining body temperature due to their larger surface area-to-mass ratio. In adults, although present in lesser amounts, brown adipose tissue remains important for those living in cold environments, continuing to function as a heat generator during exposure to cold temperatures.

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